Champions Manchester City could only muster a 2-2 Premier League draw with Brighton & Hove Albion on Saturday.
Barcelona and Manchester United clash in the Champions League final at Wembley on Saturday (1845 GMT) to decide who are the undisputed kings of Europe.
Mohamed Salah's 100th Premier League goal helped Liverpool cruise to a 3-0 victory at 10-man Leeds United on Sunday in a match that was marred by a nasty injury to teenager Harvey Elliott.
A preview of the line-up action in the English Premier League.
Chelsea also begin the new English season at home, against promoted Birmingham City.
Chelsea blinked first in the race for the Premier League title on Sunday, letting slip two points in a 1-1 draw at Blackburn as champions Manchester United enjoyed a two-point cushion at the top of the table.
Chelsea's Belgium forward won Eden Hazard England's PFA player of the year award ahead of Tottenham Hotspur's Harry Kane and Manchester United goalkeeper David De Gea on Sunday.
A summary of Wednesday's Champions League Round of 16, Second Leg, matches.
Manchester United may soon follow in the footsteps of other Premier League clubs like Liverpool and Newcastle. The club is on the threshold of being resold. A sovereign wealth fund from Qatar has evinced an interest to take control at Old Trafford.
Manchester United stormed to the top of the Premier League on Saturday with a 4-1 thumping of Middlesbrough as Chelsea stole the limelight with a 6-0 hammering of third-placed Manchester City.
Liverpool players hail Juergen Klopp impact after defeating City.
Brighton kept a disciplined formation, frustrating Liverpool and as the second half wore on the home side began to lose their fluency.
City completed the treble of Champions League, Premier League and FA Cup titles, matching Manchester United's feat in 1999 and drawing comparisons with Guardiola's 2008-09 Barcelona team.
Manchester United, buoyed by five successive Premier League victories, head into Sunday's derby against Manchester City a place and a point above their rivals and believing they are poised to restore red ascendancy in the city.
The Premier League leaders will be without Rio Ferdinand, Gary Neville, Nemanja Vidic and Mikael Silvestre for their Champions League semi-final against Inter Milan.
Antonio Valencia's early thunderbolt put Manchester United en route to a 4-0 Premier League victory over Everton on Sunday, but they needed a flurry of late goals to finally subdue their unfortunate visitors.
Images from the English Premier League matches played on Saturday
Ronaldo back for Man Utd but injured Shaw faces weeks out
Manchester United moved to the top of the Premier League with a comfortable 2-1 win over Arsenal, a match that saw striker Robin van Persie face his old side for the first time.
Manchester United moved to the top of the Premier League with a comfortable 2-1 win over Arsenal, a match that saw striker Robin van Persie face his old side for the first time.
Manchester United fielded a defence boasting only two first-team appearances but still proved too good for Premier League rivals Newcastle United with a 2-1 win in the League Cup third round at Old Trafford on Wednesday.
IMAGES from the English Premier League matches played on Sunday.
Manchester United striker Michael Owen has agreed a one-year contract extension, the Premier League champions said on Wednesday.
Manchester United beat Bolton Wanderers 2-1 to go three points clear in the premier league.
Spurs Premier League match at Brighton postponed due to COVID-19
Premier League leaders Leicester City moved even closer to the title by winning 2-0 at relegation-threatened Sunderland on Sunday. England international Jamie Vardy put them ahead in the 66th minute and he added his second -- and 21st of the season -- in added time. That left them 10 points ahead of second-placed Tottenham Hotspur, who play Manchester United later on Sunday. With five games left, Claudio Ranieri's unfashionable side need a maximum of nine more points to become English champions for the first time. Sunderland remain in the bottom three, four points behind Norwich City, who they play next Saturday. "It was tough, we knew it would be, but we ground it out," Vardy told Sky Sports. "We know it's a step closer but you never know what can happen. "The main thing now is we've got to take it into the next week."
An injury-time goal from Fulham's Darren Bent inflicted more pain on struggling Manchester United as the bottom club rescued a 2-2 Premier League draw on Sunday while Tottenham Hotspur beat top-four rivals Everton 1-0.
West Ham United piled more misery on managerless Tottenham Hotspur by coming from behind to book their place in the League Cup semi-finals with a 2-1 win at White Hart Lane and Manchester United also reached the last four on Wednesday.
Manchester United may be the bookies' favourites to defend their Premier League crown but after a summer of big spending there are no safe bets this season.
The United fans, who celebrated the victory at the end of the game with the manager and players, have not been the source of criticism of Solskjaer -- indeed the Norwegian has enjoyed strong backing from supporters who attend games at Old Trafford and those who travel away.
Chelsea put a miserable week behind them to return to the Premier League summit with a 2-0 win over Fulham as the wheels came off Liverpool's bright start in a 1-0 home defeat to Southampton on Saturday.
Images from Tuesday's action in the Premier League
Manchester United will carry the hopes of an all-English Champions League final with them this week when they host AC Milan and Chelsea face Liverpool at Stamford Bridge.
Liverpool should not be considered favourites when they travel to face Manchester City in the Premier League on Sunday, manager Juergen Klopp said on Friday, despite his side's impressive record against teams near the top of the table.
A turbo-charged start yielding two goals in the opening 15 minutes and a spectacular effort by Tom Cleverley led Manchester United to a 3-0 victory at Newcastle United in the Premier League on Sunday.
Manchester United smashed the British transfer record when they signed Argentina winger Angel Di Maria from Real Madrid for 59.7 million on Tuesday.
Arsenal scored twice in the opening seven minutes and ended the match as a contest with a third in the 19th as they crushed Manchester United 3-0 to move above them into second place in the Premier League at the Emirates on Sunday.
Newcastle United's clash with AFC Wimbledon was postponed after flooding damaged the Wimbledon pitch on Monday.
IMAGES from the EPL matches played on Saturday